hpmanager.exe is a mass-mailing worm W32.Mytob.KE@mm. hpmanager.exe opens a back door on TCP port 27999. hpmanager.exe tries to terminate antiviral programs installed on a user computer. Related files: %System%\hpmanager.exe Adds the value: "Hewlett Packard Manager" = "hpmanager.exe" to the Windows startup registry keys. More info: http://securityresponse.symantec.com/avc... Removal: Kill hpmanager.exe process and remove hpmanager.exe from Windows startup using antivirus (also check How To Remove section)Startup Optimizer.
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