mshotmon.exe is a mass-mailing worm W32.Mytob-FL. mshotmon.exe opens a back door on IRC channels. mshotmon.exe tries to terminate antiviral programs installed on a user computer. Related files: %System%\mshotmon.exe More info: http://www.sophos.com/virusinfo/analyses... Removal: Kill mshotmon.exe process and remove mshotmon.exe from Windows startup using antivirus (also check How To Remove section)Startup Optimizer.