picx.exe is a mass-mailing worm W32.Mytob.KP@mm. picx.exe opens a back door on TCP port 3385. picx.exe tries to terminate antiviral programs installed on a user computer. Related files: %System%\picx.exe Adds the value: "PIC SYSTEM" = "picx.exe" to the Windows startup registry keys. More info: http://securityresponse.symantec.com/avc... Removal: Kill picx.exe process and remove picx.exe from Windows startup using antivirus (also check How To Remove section)Startup Optimizer.