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I experienced a similar problem, though I could see the explorer window, it was covered by the Data Execution Prevention (DEP) message. I didn't expect it to be a virus, as my XPSP2 computer is equipped with current firewall and anti-virus, et al. However, I did not want to disable DEP, fearing that something may really be there!
After trying multiple fixes, found through other internet searches, including DiskClean, RegCure, chkdsk, SFC/SCANNOW, McAfee Stinger, none worked, although RegCure, after several cycles, solved the problem for a little while, DEP would be encountered trying to open the Control Panel, perform a file search, or open windows explorer.
Upon looking to see what information would be transmitted to Microsoft due to the system error, the technical information stated (in part):
Event Type: BEX, P1: explorer.exe, P4: PnEL.dll
Another internet search revealed that PnEL.dll is apparently a component of Earthlink software. I was able to remove Earthlink software from my machine (working behind the DEP window), and the problem appears to be solved!
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