If you are using anything other than Xp, you can uninstall it or reinstall. In xp, IE is integral to the operating system so uninstalling it is not an option. My advice to you is not to use IE. Use an alternate browser that can be uninstalled and installed. There are many and it can save you head aches.
Good alternate browsers are Opera, Mozilla, Firefox. Some based on IE are Slimbrowser, Maxthon, Green, Crazy, and Avant.
http://support.microsoft.com/default.aspx?kbid=318378