Just ran across a beta program called Gladiator www
www.gladiator-antivirus.com . It took some effort to get it working, but it unpacks zipped files, warns on programs that can exchange information via the web and was the first program I've tried that even caught the Eicar test message. My Etrust and AVG do not catch the test.
I tried Bullguard
www.bullguard.com, but it tries privacy tricks and drives you crazy with popup notices, and if you turn off the popups, you might lose access to some sites as it blocks their cookies.
I've been using two or more AV programs for about 5 years now and the only time I had a problem was a conflict with PCCillin and another program that I was testing out, when running Black Ice Defender at the same time.
My position on using two AV programs is that it can be done seamlessly, but this does not preclude having a good firewall, using an anti-trojan program plus Adaware, Spybot S&D and perhaps Pest Patrol and you will be about as safe as you can get.
I've never been infected by a virus, at least noty since my DOS days in '88.
I check for updates daily on all.
I've seen a num,ber of AV testing results included those posted in this forum, but have also read numerous articles saying that there are no bullet proof antivirus programs.