I have one game on my computer that effectively "disables" the screen saver. Whenever I play that game if I don't go into Display Settings, set it to another screen saver (to activate the Apply button) then set it back to the "Blank" screensaver I prefer, the screen saver will not kick on. If I do that routine, the screensaver will work perfectly until the next time I play that game.
I've never found a cure for the problem...other than not playing that particular game, that is.
Of course, screen savers are just eye candy. Modern monitors don't really need them although I've read that LCD screens can get images "burned in" if left on long enough with the same high-contrast graphics on. I don't know if that's true.