Hey,
You can restore IE's settings by going into regsvr32 shdocvw.dll
make sure you have enabled the JIT in the Advanced Settings under Internet Options under Microsoft VM.
Have you tried using the IE Repair Tool? Open Control Panel -> ADD/REMOVE Programs -> Microsoft Internet Explorer
Click the Add/Remove button and select Repair Internet Explorer. Follow the instructions which will include a RESTART.
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Disable any popup stopper ect on your computer.
http://beam.to/spybotsd this has proven to be the best help in removing your problem run this and you hopefully wont have the problem again.
Hope it helps.
Fraz.