You probably only use a handful of them. I suggest moving some you never use into another folder. You won't be able to access the fonts in Word or Notepad.
Create a New Folder by right clicking on desktop. New>Folder.
Open "Fonts" in Control Panel. Switch to Classic View to find them easier.
Highlight a group of fonts younever use and move them to the other folder. Repeat if you have tons of fonts.
Put the folder into My Documents for easy access.
Reboot and see if it starts any faster for you. If not, just copy the fonts back to the original font folder.